Proliferating cell nuclear antigen (PCNA) allows the automatic identification of follicles in microscopic images of human ovarian tissue

نویسندگان

  • Thomas W. Kelsey
  • Benedicta Caserta
  • Luis Castillo
  • W. Hamish B. Wallace
  • Francisco Cóppola Gonzálvez
چکیده

School of Computer Science, University of St. Andrews, St Andrews, Scotland, UK; Pereira Rossell Hospital, ASSE, Ministry of Public Health, Montevideo, Uruguay; Division of Child Life and Health, Department of Reproductive and Developmental Sciences, University of Edinburgh, Edinburgh, Scotland, UK; Department of Obstetrics and Gynecology C, School of Medicine, University of the Republic, Montevideo, Uruguay.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

ارزیابی فرآیند تکثیرسلولی فولیکولهای تخمدان با استفاده از تکنیک ایمونوهیستوشیمی PCNA در رت های هیپوتیروئید

Introduction & Objective: The normal females reproductive function , needs hypothalamus-hypophysis-ovarian extensive hormonal messages. Primary hypothyroidism is characterized by reduced production and secretion of thyroid hormones. During follicular growth PCNA (Proliferating Cell Nuclear Antigen) and cycklin D complex play an important role in regulating cell proliferation .This study aime...

متن کامل

Immunohistochemical localization of proliferating cell nuclear antigen (PCNA) in the pig ovary.

The aim of the study was to determine the expression of proliferating cell nuclear antigen protein (PCNA) in the pig ovary. The localization of PCNA was demonstrated in paraffin sections of pig ovarian tissue using primary mouse monoclonal anti-PCNA antibody. In primordial follicles, no remarkable staining for PCNA either in granulosa cells or in the oocytes was observed. In primary to secondar...

متن کامل

Comparison of the Expression Level of P53 and Proliferating Cell Nuclear Antigen (PCNA) Genes in the Inflamed and Non-Inflamed Dentigerous Cysts

Background & Aims: The role of P53 and proliferating cell nuclear antigen (PCNA) genes in inflamed and non-inflamed odontogenic cysts is related to cell proliferation but it is unclear. The aim of this study was immunohistochemical evaluation of P53 and PCNA expression in inflamed and non-inflamed dentigerous cysts Methods: In the present study, 23 dentigerous cysts (12 inflamed and 11 non-infl...

متن کامل

E-Cadherin in Relation with the Proliferating Cell Nuclear Antigen of the Bilharzia Associ-ated and Non-Associated Urinary Bladder Carcinoma

Background: E-cadherin is a trans-membrane glycoprotein that plays a critical role in many aspects of cell adhesion as well as establishment and maintenance of epithelial cell polarity. Loss of the adhesive function of E-cadherin seems to promote invasive and metastatic properties of neoplastic cells. Objectives: The present study is a retrospective study aiming to evaluate the loss of E-cadher...

متن کامل

Developmental Status: Impact of Short-Term Ischemia on Follicular Survival of Whole Ovarian Transplantation in a Rabbit Model

Ischemia is the first mechanism that provokes the loss of follicles in ovarian grafts over the long term. In whole ovarian transplantation, it remains unknown, however, how changes in follicular development are influenced by short-term ischemia. Fresh whole ovarian orthotopic auto-transplantation was performed in rabbits with 45 min ischemia, and the impact of ischemia on follicular survival an...

متن کامل

ذخیره در منابع من

ذخیره در منابع من قبلا به منابع من ذحیره شده

{@ msg_add @}


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • CoRR

دوره abs/1008.3798  شماره 

صفحات  -

تاریخ انتشار 2010